Found 64,776 clinical trials
Establishment of an Early Warning Screening System for Hemophagocytic Lymphohistiocytosis a Multi-center, Prospective Study
Our three-step screening system uses commonly used clinical and laboratory parameters to effectively identify patients who may be at high risk of HLH, conduct etiology screening early for patients who meet the diagnostic criteria for HLH, and guide standardized treatment. Therefore, this study proposes to establish a highly accurate and …
Observational Study on the Treatment of Patients With Metastatic Breast Cancer
This is a descriptive, retrospective, observational study to generate Real-World Evidence (RWE). This study will evaluate the treatment patterns and outcomes with metastatic or unresectable hormone receptor-positive breast cancer in Brazil. No hypotheses will be tested.
"Turkish Validation of the Respiratory Distress Observation Scale in Palliative Care"
Dyspnea is a subjective experience influenced by physiological, cognitive, behavioral, and sociocultural factors. While self-reported scales are commonly used to assess dyspnea severity, they are unsuitable for patients unable to communicate, such as those with cognitive impairment or sedation. The Respiratory Distress Observation Scale (RDOS), developed by Campbell in 2008, …
PROMs After Pancreatectomy
The standard of care for a patient with resectable pancreatic is to perform pancreatic resection which, even in the modern era is associated with significant complications and impact on quality of life, often in the setting of poor survival even in the best scenario. Currently, there is a lack of …
Canadian Bone Strength Development Study
The goal of this project is to learn about differences in bone development between children with and without type-1 diabetes (T1D). The main questions this study aims to answer are: Assess how and when sex-specific bone developmental trajectories in the leg and arm will differ between children with T1D and …
Evaluation of Clinical Results of Patients Treated Conservatively for Distal Biceps Tendon Lesions
A clinical evaluation of the results of conservative treatment after distal biceps tendon rupture with a minimum follow up of 1 year. The results will be evaluated with clinical scores (MEPS, DASH and SF-12) and strenght and fatigue evaluations with dynamometers for both flexion and supination of elbow and forearm. …
Heart Rate Variability as a Predictor of Rebound Pain Following Total Knee Arthroplasty
This study aims to investigate whether heart rate variability (HRV), a marker of autonomic nervous system activity, can predict the occurrence of rebound pain after total knee arthroplasty (TKA). Rebound pain is defined as a sudden and intense pain episode (NRS ≥7) that typically arises after the resolution of peripheral …
Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical …
Comparison of the Occurrence of Postoperative Complications Between Robotic and Laparoscopic Surgery in Revision Bariatric Surgery
In a population of patients undergoing bariatric revision surgery with conversion to RYGB and divided into two groups according to the surgical protocol: Group 1: robotic surgery Group 2: laparoscopy The primary objective of the study is to compare the rates of postoperative complications between the two groups, classified according …
SURE Trial: Swallowing Ultrasound Reliability Evaluation Trial
This study aims to explore the reliability of using ultrasonography (US) for the assessment of swallowing function in patients with dysphagia. The study will recruit 80 patients and compare the findings with those obtained from fiberoptic endoscopic evaluation of swallowing (FEES), which serves as the gold standard.
